Resume / CV

Education

Peer Reviewed Publications

First Author Peer Reviewed Publications:

1. Grunin M, Igo RP Jr, Song YE, Blanton SH, Pericak-Vance MA, Haines JL, IAMDGC. Identifying X-Chromosome Variants associated with Age-related Macular Degeneration. Hum Mol Genetics 2024 Sept

2. Grunin M, Triffon D, Beykin G, Rahmani E, Schweiger R, Tiosano L, Khateb S, Hagbi-Levi S, Rinsky B, Munitz R, Winkler TW, Heid IM, Halperin E, Carmi S, Chowers I. Genome Wide Association Study and Genomic Risk Prediction of Age-related Macular Degeneration Sci Reports 2024 June

3. Khateb S, Chowers I, Grunin M. When Opposites Attract: What Can We Learn from the Surprising Insight to the Genetic Background of AMD and CSC. JAMA Ophthalmology 2023

4. Grunin M, Kinzy TG, Cooke Bailey JN. Note the Nuance- Examining the Association of Alzheimer-Protective APOE Variation With Risk for Age-Related Macular Degeneration. JAMA Ophthalmology.   2023 Jan 1

5. Grunin M*, Palmer E*,  de Jong S*, Jin B, Rinker D, Moth C, Capra A, Haines JL+, Bush W+, den Hollander A+. Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease – Advances in Experimental Medicine and Biology May 2023

6. Waksmunski AR*, Grunin M*, Kinzy TG, Igo RP Jr, Haines JL+, Cooke Bailey JN+ (*/+ indicates equal contribution). Statistical Driver Genes as a Means to Uncover Missing Heritability for Age-related Macular Degeneration. BMC Med Genomics 2020 Jul 6

7. Grunin M, Beykin G, Rahmani E, Schweiger R, Barel G, Hagbi-Levi S, Elbaz-Hayoun S, Rinsky B, Ganiel M, Carmi S, Halperin E, Chowers I. Association of a Variant in VWA3A with Response to Anti-VEGF Treatment in Neovascular Age-Related Macular Degeneration. Invest Ophthalmol Visual Sci. 2020 Feb 7

8. Lores-Motta L*, Riaz M*, Grunin M*, Corominas J, van Asten F, Pauper M, Leenders M, Richardson AJ, Muether P, Cree AJ, Griffiths HL, Pham C, Belanger MC, Meester-Smoor MA, Ali M, Heid IM, Fritsche LG, Chakravarthy U, Gale R, McKibbin M, Inglehearn CF, Schlingemann RO, Omar A, Chen J, Koenekoop RK, Fauser S, Guymer RH, Hoyng CB, de Jong EK, Lotery AJ, Mitchell P, den Hollander AI+, Baird PN+, Chowers I+. (* and + indicate Equal Contribution). Genome-wide association study for common and rare variants on response to anti-VEGF therapy in age-related macular degeneration. JAMA Ophthalmology. 2018 May 31

9. Grunin M, Hagbi-Levi, S, Rinksy, B, Smith Y, Chowers I. Transcriptome Analysis on Monocytes from Patients with Age-Related Macular Degeneration. Sci Rep. 2016 Jul

10. Grunin M, Tiosano L, Jaouni T, Averbukh E, Sharon D, Chowers I. Evaluation of the association of single nucleotide polymorphisms in the PRPH2 gene with adult-onset foveomacular vitelliform dystrophy. Ophthalmic Genet. 2016 Feb 5

11. Grunin M, Hagbi-Levi S, Chowers I. The role of monocytes and macrophages in age-related macular degeneration. Adv Exp Med Biol. 2014

12. Grunin M, Burstyn-Cohen T, Hagbi-Levi S, Peled A, Chowers I. Chemokine receptor expression in peripheral blood monocytes from patients with neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 2012 Aug 7

    Other Peer-Reviewed Publications:

13. Elbaz-Hayoun S, Rinsky B, Hagbi-Levi S, Grunin M, Chowers I. CCR1 Mediates Muller Cell Activation and Photoreceptor Cell Death in Macular and Retinal Degeneration . ELife 2023 Oct 30

14. Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA…et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer’s disease: the Alzheimer’s Disease Genetics Consortium. medRxiv 2023 Jul 8 Preprint

15. Waksmunski A, Miskimen K, Song YE, Grunin M, Laux R, Fuzzell D, Fuzzel S, Adams LD, Caywood L, Prough M, Stambolian D, Scott WK, Pericak-Vance MA, Haines JL. Consequences of a rare complement factor H variant for age-related macular degeneration in the Amish. IOVS 2022 Aug 2.

16. Bellenguez C, Kucukali F, Jansen IE….Grunin M…..et al. New Insights into the Genetic Etiology of Alzheimer’s Disease and Related Dementias. Nature Genetics 2022 Apr 4

17. Rinsky B, Beykin G, Grunin M, Amer R, Khateb S, Tiosano L, Almeida D, Hagbi-Levi S, Elbaz-Hayoun S, Chowers I. Analysis of the Aqueous Humor Proteome in Patients with Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2021 Aug 2

18. Hagbi-Levi S, Tiosano L, Rinsky B, Levinger N, Elbaz-Hayoun S, Grunin M, Chowers I. Anti-tumor necrosis factor alpha reduces the pro-angiogenic effects of activated macrophages derived from patients with age-related macular degeneration. Mol Vision 2021

19. Levinger N, Beykin G, Grunin M, Almeida D, Levy J, Levine H, Averbukh E, Chowers I. Socioeconomic Status and Visual Outcome in Patients with Neovascular Age-Related Macular Degeneration. Eur J Ophthalmol 2020 May 4

20. Elbaz-Hayoun S, Rinsky B, Hagbi-Levi S, Grunin M, Haya Yedid T, Chowers I. Evaluation of Antioxidant Treatments for the Modulation of Macrophage Function in the Context of Retinal Degeneration. Mol Vision, 2019 Sep 5

21. Waksmunski AR, Grunin M, Kinzy TG, Igo RP Jr, Haines JL, Cooke Bailey JN, IAMDGC. Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration. IOVS, 2019 Sept 3

22. Hagbi-Levi S, Abraham M, Tiosano L, Rinsky B, Grunin M, Eizenberg O, Peled A, Chowers I. Promiscuous Chemokine Antagonist (BKT130) Suppresses Laser-Induced Choroidal Neovascularization by Inhibition of Monocyte Recruitment. J Immunology Research 2019 Aug 5

23. Rinsky, B. Hagbi-Levi S, Elbaz Hayoun S, Grunin M, Chowers I. Characterizing the effect of supplements on the phenotype of cultured macrophages from patients with age-related macular degeneration. Molecular Vision, Dec 2017

24. Hagbi-Levi S, Grunin M, Jaouni T, Tiosano L, Rinsky B, Elbaz-Hayoun S, Peled A, Chowers I. Pro- Angiogenic Characteristics of Activated Macrophages from Patients with Age-related Macular Degeneration. Neurobiology of Aging Dec 9, 2016

25. Tiosano L, Grunin M, Hagbi-Levi S, Banin E, Averbukh E, Chowers I. Characterising the phenotype and progression of sporadic adult-onset foveomacular vitelliform dystrophy. Br J Ophthalmol. 2016 Jan 22

26. Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R, Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE, Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G, Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M, Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I, Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S, Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP Jr, Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B, Merriam JC, Smith RT, Khan JC, Shahid H, Moore AT, McGrath JA, Laux R, Brantley MA Jr, Agarwal A, Ersoy L, Caramoy A, Langmann T, Saksens NT, de Jong EK, Hoyng CB, Cain MS, Richardson AJ, Martin TM, Blangero J, Weeks DE, Dhillon B, van Duijn CM, Doheny KF, Romm J, Klaver CC, Hayward C, Gorin MB, Klein ML, Baird PN, den Hollander AI, Fauser S, Yates JR, Allikmets R, Wang JJ, Schaumberg DA, Klein BE, Hagstrom SA, Chowers I, Lotery AJ, Léveillard T, Zhang K, Brilliant MH, Hewitt AW, Swaroop A, Chew EY, Pericak- Vance MA, DeAngelis M, Stambolian D, Haines JL, Iyengar SK, Weber BH, Abecasis GR, Heid IM. A large genome- wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nature Genetics. 2016 Feb

27. Hagbi-Levi S, Grunin M, Elbaz-Hayoun S, Tal D, Obolensky A, Hanhart J, Banin E, Burstyn- Cohen T, Chowers I. Retinal Phenotype following Combined Deletion of the Chemokine Receptor CCR2 and the Chemokine CX3CL1 in Mice. Ophthalmic Res. 2016

28. Beykin G, Grunin M, Averbukh E, Banin E, Hemo Y, Chowers I. Bevacizumab treatment for neovascular age-related macular degeneration in the setting of a clinic: "real life" long-term outcome. BMC Ophthalmol. 2015 Apr 11

29. Chowers I, Tiosano L, Audo I, Grunin M, Boon CJ. Adult-onset foveomacular vitelliform dystrophy: A fresh perspective. Prog Retin Eye Res. 2015 Jul

30. Tiosano L, Jaouni T, Averbukh E, Grunin M, Banin E, Chowers I. Bevacizumab treatment for choroidal neovascularization associated with adult-onset foveomacular vitelliform dystrophy. Eur J Ophthalmol. 2014 Nov-Dec

31. Lederman M, Hagbi-Levi S, Grunin M, Obolensky A, Berenshtein E, Banin E, Chevion M, Chowers I. Degeneration modulates retinal response to transient exogenous oxidative injury. PLoS One. 2014 Feb 21

32. Jaouni T, Averbukh E, Burstyn-Cohen T, Grunin M, Banin E, Sharon D, Chowers I. Association of pattern dystrophy with an HTRA1 single-nucleotide polymorphism. Arch Ophthalmol. 2012 Aug

33. Lederman M, Obolensky A, Grunin M, Banin E, Chowers I. Retinal function and structure in the hypotransferrinemic mouse. Invest Ophthalmol Vis Sci. 2012 Feb 2

    Consortia Related Articles as part of the IAMDGC

34. Grover S, Sharma M, IAMDGC. Sleep, Pain and Neurodegeneration: A Mendelian Randomization Study. Front Neurol. 2022

35. Gorman BR, Voloudakis G, Igo RP, Kinzy T, Halladay CW, Bigdeli TB, Venkatesh S, Cooke Bailey JN, Crawford DC, Markianos K, Dong F, Schreiner P, Zhang W, VA Million Veterans Program, IAMDGC, Hadi T, Anger MD, Stockwell AD, Melles RB, Yin J, Choquet H, Kaye R, Patasova K, Patel PJ, Yaspan BJ, Jorgenson E, Hysi PG, Lotery AJ, Gaziano JM, Tsao PS, Fliesler SJ, Sullivan JM, Greenberg PB, Whu WC, Assimes TL, Pyarajan S, Roussos P, Peachey NS, Iyengar SK. Distinctive Cross-ancestry Genetic Architecture for Age-related Macular Degeneration. medRxiv ahead of print doi: https://doi.org/10.1101/2022.08.16.22278855

36. Biasella F, Strunz T, Kiel C, IAMDGC, Weber BHF, Friedrich U. Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD. Cells 2022

37. Kuan V, Warwick A, Hingorani A, Tufail A, Cipriani V, Burgess S, Sofat R, IAMDGC. Association of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index and Glycemic Risk Factors with Age-Related Macular Degeneration: A Mendelian Randomization Study. JAMA Ophthalmology 2021 Dec 1

38. Strunz T, Lauwen S, Kiel C, IAMDGC, Hollander AD, Weber BHF. A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration. Sci Rep 2020 Jan 31

39. Grassmann F, Kiel C, Zimmermann ME, Gorski M, Grassmann V, Stark K, IAMDGC, Heid IM, Weber BH. Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits. Genome Med 2017 Mar 27

Publications under review/unpublished YET:
1.       Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemor K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin M, Leung YY, Kuksa PP, Li D, da Fonseca L, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker TJ, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goat AM, Grabowski TJ, Graff-Radford G, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Kathyrn LL, Lyketsos CG, Mains D, Margaret FE, Marson D, Martin ER, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O’Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Silfer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Tronscoso JC, Tsuang DW, Deerlin VMV, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhemsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wrigth CB, Wu CK, Younkin SG, Yu SE, Yu L, Xiongwei Z, Kunkle B, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericack-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer’s disease: the Alzheimer’s Disease Genetics Consortium. medRxiv 2023 Jul 8: Under Review by Nature Genetics

4.       Grunin M*, de Jong S*, Palmer E*, Jin B, Rinker D, Moth C, Capra A, Haines JL+, Bush WS+, den Hollander AI+. Spatial Modeling of Variants in Complement Genes Associated with AMD. (*/+ indicates equal contribution). medRxiv 2023

5.       Chung J, Sun X, Schmidt M, Song YE, Grunin M, Palmer E, Bush WS, Naj AC, Rajabli F, Hamilton-Nelson KL, Zhang X, Leung YY, Li-San W, Mayeux R, Schellenberg GD, Pericak-Vance MA, Haines JL*, Farrer LA, Kunkle BW, Martin ER. Variants near X-Chromosome Genes NLGN4X and PTCHD1 are Significantly Associated with Alzheimer’s Disease Risk. Alzheimer’s and Dementia Abstract – in advanced prep

6.       Grunin M, Wheeler NR, Bush WS, Haines JL*, Alzheimer Disease Sequencing Project .Using Linkage Analysis to Identify Novel Gene-Gene Interactions in Alzheimer’s Disease. Alzheimer’s and Dementia Abstract. – in advanced prep

7.       Grunin M*, Gorski M*, He KY, Igo RP, Song YE, Zhu X, Heid IM+, Haines JL+, IAMDGC. Dense SNP IAMDGC Dataset Developed Through Imputation. (*/+ indicates equal contribution) - under review

8.       Vofo BN, Schwartz Y, Jaskoll S, Kramer A, Elbaz-Hayoun S, Rinsky B, Grunin M, Cnaany Y, Tiosano L, Chowers I. Long-term Macular Atrophy Growth in Neovascular Age-related Macular Degeneration: Influential Factors and Role of Genetic Variants. Under Review by Ophthalmology Retina.

Presentations

First/Last Author Oral/Lecture Presentations:

1. Grunin M*, Igo RP Jr, Song YE, Blanton S, Pericak-Vance M, Haines JL, IAMDGC. Identifying X-Chromosome Variants Associated with Age-related Macular Degeneration. ISVER (ARVO Affiliate). Haifa, Israel, March 2, 2023.

2. Grunin M*, de Jong S*, Palmer E*, Jin B, Rinker D, Moth C, Capra A, Haines JL+, Bush W+, den Hollander A+. Spatial Modeling of Variants in Complement Genes Associated with Age-related Macular Degeneration: (*/+ indicates equal contribution) FISEB/ILANIT (Feb 2023) Eilat, Israel

3. Grunin M*,de Jong S*, Palmer E*,Jin B, Rinker D, Moth C, Capra A, Haines JL+, Bush W+, den Hollander A+. Spatial Analyses of Complement Factor Genes Associated with Age-related Macular Degeneration: (*/+ indicates equal contribution) The Association for Research in Vision and Ophthalmology (ARVO) (May 3, 2022) Denver, CO, USA

4. Grunin M*, de Jong S*, Palmer E*, Jin B, Rinker D, Moth C, Capra J, Haines JL+, Bush WS+, den Hollander AI+ (*/+ indicate equal contribution). Spatial Modeling of Variants in Complement Genes Associated with Age-related Macular Degeneration. (2021 Oct 1) . The XIX International Symposium for Retinal Degenerations (RD2021). Nashville, TN, USA.

5. Grunin M, He KY, Igo RP Jr, Song YE, Gorski M, Heid IM, Wheeler NR, Bush WS, Zhu X, Pericak-Vance MA, Haines JL, IAMDGC Corporate Author. Dense SNP IAMDGC Dataset Developed Through Imputation. 2021 March. The Israel Society for Vision and Eye Research, Israel* (canceled in person due to COVID19)

6. Grunin M, He KY, Igo RP Jr, Song YE, Gorski M, Heid IM, Zhu X, Haines JL, IAMDGC Corporate Author. Dense SNP IAMDGC Dataset Developed Through Imputation. (2020 May The Association for Research in Vision and Ophthalmology (ARVO), Baltimore MD* (canceled in person due to COVID-19).

7. Waksmunski AR*, Grunin M*, Kinzy TG, Igo RP Jr, Haines JL+, Cooke Bailey JN+, IAMDGC. (*/+ indicates equal contribution) Statistical Driver Genes and the Missing Heritability of Age-related Macular Degeneration. (2020 May The Association for Research in Vision and Ophthalmology (ARVO), Baltimore MD* (canceled in person due to COVID-19).

8. Grunin M, Beykin G, Rahmani E, Schweiger R, Barel G, Hagbi-Levi S, Rinsky B, Halperin E, Chowers I. (2016- March 9-10) Pharmacogenetic Analysis of Patients with Neovascular Age- Related Macular Degeneration. The 36th Annual Conference of the Israel Society for Vision and Eye Research (ISVER-ARVO-affilliate), Israel. Lecture presentation.

9. Grunin M, Tiosano L, Rahmani E, Beykin G, Schweiger R, Hagbi-Levi S, Sharon D, Halperin E, Chowers I. (2015- March 13-14). Genome Wide Association Study Analysis on Adult Onset Foveomacular Vitelliform Dystrophy in the Israeli Population. The 35th Annual Conference of the Israel Society for Vision and Eye Research (ISVER-ARVO-affilliate), Israel. Lecture presentation.

10. Grunin M, Tiosano L, Jaouni T, Hagbi-Levi S, Sharon D, Chowers I. (2014- March 27-28) Single Nucleotide Polymorphic Changes in Patients with Adult Onset Foveal Vitelliform Dystrophy. The 34nd Annual Conference of the Israel Society for Vision and Eye Research (ISVER-ARVO affiliate), Israel. Lecture presentation.

11. Grunin M, Hagbi-Levi S, Mosqueda P, Beykin G, Amer R, Chowers I. (2014- March 27-28) Analysis of Gene Expression in Monocytes from Patients with Age-related Macular Degeneration. The 34nd Annual Conference of the Israel Society for Vision and Eye Research (ISVER-ARVO affiliate), Israel. Lecture presentation.

12. Grunin M, Burstyn-Cohen T, Hagbi-Levi S, Peled A, Chowers I (2012- Jul 16-21). Characterizing Monocyte Recruitment Signals in White Blood Cells from Patients with Age- Related Macular Degeneration. XVth International Symposium on Retinal Degeneration (RD2012), Bad Gogging, Bavaria, Germany. Lecture presentation.

13. Grunin M, Burstyn-Cohen T, Peled A, Chowers I. (2011- Mar 24-25) Chemokine Receptor Expression in White Blood Cell Sub-Populations from Patients with Age-related Macular Degeneration. The 31st Annual Conference of the Israel Society for Vision and Eye Research (ISVER-ARVO affiliate), Israel. Abstract No. 83, Lecture presentation.

Consortia Oral Presentations:

1. Grunin M, He KY, Igo RP Jr, Song YE, Gorski M, Heid IM, Wheeler NR, Bush WS, Zhu X, Pericak-Vance MA, Haines JL, IAMDGC. Update on TOPMed Imputation. IAMDGC consortium meeting. (Sept 20, 2022). Belfast, Ireland

2. Grunin M, He KY, Igo RP Jr, Song YE, Gorski M, Heid IM, Wheeler NR, Bush WS, Zhu X, Pericak-Vance MA, Haines JL, IAMDGC. Dense SNP IAMDGC Dataset Developed through Imputation. IAMDGC Consortium Meeting (Nov 9, 2020)* Canceled in Person due to COVID19

3. Grunin M, as part of T32 Grant: Visual Sciences Training Program. Genetic Analysis of AMD with the IAMDGC. (June 12, 2020) CWRU, Cleveland, OH, USA* Canceled in Person due to COVID19

4. Grunin M, Wheeler NR, Bush WS, Haines JL, ADSP. Using Linkage Analysis to Identify Novel Gene-Gene Interactions in Alzheimer’s Disease. (Feb 25, 2020) Alzheimers Disease Genetics Consortium Conference (ADGC). Philadelphia, PA, USA.

5. Grunin M, He K, Song YS, Igo RP Jr, Zhu X, Haines JL, IAMDGC – TOPMed Imputation of the IAMDGC Data (Nov 6 2019) International Age-Related Macular Degeneration Genomics Consortium Conference (IAMDGC) Mishkenot Shaananim, Jerusalem, Israel

6. Grunin M, Beykin G, Rahmani E, Schweiger R, Tiosano L, Khateb S, Hagbi-Levi S, Rinsky B, Carmi S, Halperin E, Chowers I – Update from Israel – GWAS of the Jerusalem Samples with AMD (Nov 6 2019) International Age-Related Macular Degeneration Genomics Consortium Conference (IAMDGC) Mishkenot Shaananim, Jerusalem, Israel

7. Grunin M, Haines JL, IAMDGC. (2018 Nov 2). Association of Variants on the X Chromosome with Age-related Macular Degeneration. International Age-Related Macular Degeneration Genomics Consortium Conference (IAMDGC), Royal Society, London, England. Lecture Presentation.

8. Grunin M, Haines, JL, IAMDGC. (2018 Oct 19). Association of Variants on the X Chromosome with Age-related Macular Degeneration. American Society of Human Genetics (ASHG), San Diego, CA, USA. Poster Presentation.

9. Grunin M, Lores de Motta L, Riaz M, Baird P, den Hollander A, Chowers I. All acknowledged equal contributors.-Pharmacogenetics on response to anti-VEGF in nvAMD.(Nov 11-12, 2016). International AMD Genomics Consortium Conference, Deer Valley, Utah, USA.

First/Last Author Poster Presentations:

1. Grunin M*, Igo RP Jr, Song YE, Blanton S, Pericak-Vance M, Haines JL, IAMDGC. Identifying X-Chromosome Variants Associated with Age-related Macular Degeneration. (April 25, 2023). The Association for Research in Vision and Ophthalmology (ARVO) New Orleans, LO, USA.

2. Palmer E*,de Jong S*, Grunin M*, Jin B, Rinker D, Moth C, Capra J, Haines JL+, Bush WS+, den Hollander AI+ (*/+ indicate equal contribution). Spatial Modeling of Variants in Complement Genes Associated with Age-related Macular Degeneration. (2021 Oct) . American Society for Human Genetics (canceled in person due to COVID19)

3. Grunin M, Wheeler NR, Bush WS, Haines JL, Alzheimer Disease Sequencing Project (2020 July 27). Using Linkage Analysis to Identify Novel Gene-Gene Interactions in Alzheimer’s Disease. (March 9-14 2021) Alzheimers Disease/Parkinson Disease Conference (AD/PD). Barcelona* (Canceled in person due to COVID19).

4. Grunin M, He KY, Igo RP Jr, Song YE, Gorski M, Heid IM, Wheeler NR, Bush WS, Zhu X, Pericak-Vance MA, Haines JL, IAMDGC. (2020 Oct). Dense SNP IAMDGC Dataset Developed Through Imputation. American Society for Human Genetics (ASHG). San Diego CA*(Canceled in person due to COVID19).

5. Grunin M, Wheeler NR, Bush WS, Haines JL, Alzheimer Disease Sequencing Project (2020 July 27). Using Linkage Analysis to Identify Novel Gene-Gene Interactions in Alzheimer’s Disease. Alzheimer Association International Conference (AAIC). Amsterdam* (Canceled in person due to COVID19).

6. Grunin M, Wheeler NR, Bush WS, Haines JL, Alzheimer Disease Sequencing Project (2019 Oct 28) Using Linkage Analysis to Identify Novel Gene-Gene Interactions In Alzheimer’s Disease. American Society for Human Genetics (ASHG), Houston TX. Poster Presentation

7. Grunin M, Wheeler NR, Bush WS, Haines JL, Alzheimer Disease Sequencing Project (2019 Aug 26) Using Linkage Analysis to Identify Novel Gene-Gene Interactions in Alzheimer’s Disease. Cleveland Brain Health Intitiative (CBHI), Cleveland Ohio. Poster Presentation.

8. Chowers I, Hayoun S, Rinsky B, Hagbi-Levi S, Grunin M. Phenotype of Macrophages from Patients with Age-related Macular Degeneration (AMD). (2019 April 28). The Association for Research in Vision and Ophthalmology (ARVO) Vancouver DC. Poster Presentation

9. Grunin M, Haines JL, IAMDGC (2019 April 28). Association of Variants on the X Chromosome with Age-related Macular Degeneration . Case Western Reserve University ShowCASE, Cleveland Ohio. Poster Presentation

10. Grunin M, Haines JL, IAMDGC (2018 Oct 19). Association fo Variants on the X Chromosome with Age-related Macular Degeneration. American Society for Human Genetics (ASHG), San Diego CA. Poster Presentation

11. Grunin M, Beykin G, Rahmani E, Schweiger R, Barel G, Hagbi-Levi S, Hayoun S, Rinsky B, Ganiel M, Carmi S, Halperin E, Chowers I. (2018 April 29-May 3) Association of a Variant in VWA3A with Response to Anti-VEGF Treatment in Neovascular Age-Related Macular Degeneration. The Association for Research in Vision and Ophthalmology (ARVO), Hawaii, HI, USA. Poster Presentation.

12. Grunin M*, Lores-Motta L*, Riaz M*, Corominas J, Richardson A, Fauser S, Guymer R, de Jong E, Heid I, Hoyng C, Lotery A, Mitchell P, Baird P+, den Hollander A+, Chowers I+. (2017- May 7- 11th) Identification of a Novel Variant Associated with anti-VEGF response in Age-related Macular Degeneration Using Exome Chip Analysis. The Association for Research in Vision and Ophthalmology (ARVO), Baltimore, MD, USA. Poster Presentation. (* or + indicates equal contribution)

13. Beykin G*, Grunin M*, Levi S, Rinsky R, Elbaz-Hayoun S, Chowers I. (2017- May 7-11th) Genome Wide Association Analysis for Sub Retinal Drusenoid Deposits. The Association for Research in Vision and Ophthalmology (ARVO), Baltimore, MD, USA. Poster Presentation. (* indicates equal contribution)

14. Chowers I, Beykin G, Rahmani E, Schweiger R, Tiosano L, Khateb S, Hagbi-Levi S, Rinsky B, Carmi S, Halperin E, Grunin M. (2017- May 7-11th) Whole-Genome Association Study of Age- related Macular Degeneration in the Israeli Population. The Association for Research in Vision and Ophthalmology (ARVO), Baltimore, MD, USA. Poster Presentation.

15. Grunin M, Tiosano, L, Jaouni T, Hagbi-Levi S, Averbukh E, Sharon D, Chowers I. (2015- May 3-7). Genetic Analysis of Adult-Onset Foveomacular Vitelliform Dystrophy. The Association for Research in Vision and Ophthalmology (ARVO), Denver, CO, USA. Poster Presentation.

16. Grunin M, Levi S, Burstyn-Cohen T, Chowers I (2013- May 5-9). Gene Expression Signature in the Monocyte Population of Patients with Age-related Macular Degeneration. The Association for Research in Vision and Ophthalmology (ARVO), Seattle, WA, USA. Poster presentation.

17. Grunin M, Hagbi-Levi S, Burstyn-Cohen T, Amar R, Beykin G, Mosqueda P, Chowers I. (2013- Mar 14-15) Gene Expression Patterns in Monocytes Isolated from Patients with Neovascular Age- related Macular Degeneration. The 33nd Annual Conference of the Israel Society for Vision and Eye Research (ISVER-ARVO affiliate), Israel. Poster presentation.

18. Grunin M, Horowitz S, Hagbi-Levi S, Burstyn-Cohen T, Chowers I. (2013- Mar 14-15) Identification of the rd8 Mutation in Commonly Used Mouse Models for Retinal Degeneration and Diseases. The 33nd Annual Conference of the Israel Society for Vision and Eye Research (ISVER- ARVO affiliate), Israel. Poster presentation.

19. Grunin M, Hagbi-Levi S, Burstyn-Cohen T, Chowers I (2012- Mar 15-16). Gene Expression Signature in the Monocyte Population of Patients with Neovascular Age-Related Macular Degeneration. The 32nd Annual Conference of the Israel Society for Vision and Eye Research (ISVER-ARVO affiliate), Israel. Poster presentation.

20. Chowers I, Grunin M, Peled A, Burstyn-Cohen T. (2011) Chemokines Receptors Expression in White Blood Cells Sub-Populations from Patients with Age-related Macular Degeneration. The Association for Research in Vision and Ophthalmology Annual Conference (ARVO), Ft. Lauterdale, FL, USA. Poster No. 423

Ad Hoc Journal Peer-Reviewer For:

New England Journal of Medicine, JAMA Ophthalmology, Computers in Biology and Medicine, Genes, Wellcome Trust, PLOS One, Therapeutic Advances for Chronic Disease, Scientific Reports, European Journal of Ophthalmology, International Journal of Molecular Sciences, PLOS Genetics

References